MadWolf Technologies has conducted exhaustive market analysis of existing Commercial Off The Shelf (COTS) Peer Review Systems to identify additional features offered by the market leaders in this sector that could prove useful for The Journal of Biological Chemistry purposes. The proposed upgrade will combine the existing functionality with the most relevant additional features offered by the eight leading COTS vendors. American Society for Biochemistry and Molecular Biology envisions the modernization and functional upgrade of its present Lotus Notes based Manuscript Tracking and Review System (MTS) and of its Online Submission and Review System (OSRS).  Both systems are robust and functioning, but lack essential modern productivity and usability features that have become available through new releases of Notes and various third party technologies.  MadWolf Technologies expertise in this area provided ASBMB with crucial and thorough market analysis.